The use of available sensors to identify body movement patterns, specific to motor changes in neurodegenerative diseases (for example in PD we are interested in tremor, bradykinesia, gait impairments and physical activity).
The design and testing of new sensors to identify their optimal configuration for detecting the described motor phenomena.
The design and development of a new portable movement analysis system, supporting neurodegenerative and PD patients.
The determination and standardization of the most convenient number and location of sensors as well as the best recording parameters of the movement analysis system.
The use of the optimized system in clinical studies on free moving patients to characterize fluctuations in their motor performance.
The exploitation of already existing databases (Electronic Patient Records Databases), extracting all the features related to common symptoms of neurodegenerative diseases.
The development of a database of movement signatures abnormalities of neurodegenerative and PD patients performing typical daily activities, and its combination with existing knowledge.
The design of algorithms for the detection and analysis of gait, tremor, body posture and bradykinesia.
Finally, the use of objective parameters provided by the final system to detect motor status (more specifically, in PD the “on” and “off’ states and motor blocks or “freezing”) in free moving patients.
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